2. Signaling Pathways
  3. MAPK/ERK Pathway
  4. Mixed Lineage Kinase
  5. Mixed Lineage Kinase Ligand

Mixed Lineage Kinase Ligand

Mixed Lineage Kinase Ligand (1):

Cat. No. Product Name Effect Purity
  • HY-182344
    MLKL ligand-2
    		Ligand
    MLKL ligand-2 is a mixed lineage kinase domain-like pseudokinase (MLKL) PROTAC ligand with a KD of 9.408 μM. MLKL ligand-2 forms hydrogen bond networks and hydrophobic interactions with specific MLKL residues, and stabilizes MLKL in hepatic cells. MLKL ligand-2 can be used to synthesize PROTAC MLKL Degrader-3 (HY-182343).